Preanalytical Variables in Coagulation Testing

This Medical Laboratory Science lesson in Hematology supports laboratory science learning and laboratory interpretation for medical laboratory students and professionals.

3.2% citrate collection, 9:1 fill ratio, underfilled tubes, hematocrit-related citrate dilution, processing and storage . CLSI H21-A5 aligned overview.

Intermediate30 min read21 sectionsHematology
Section 1 of 210%

Learning Objectives

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Section 1 of 21

Learning Objectives

Learning Objectives

Section: Learning Objectives

Coagulation assays are screening tools, interpret with specimen quality, reagent context, and institutional reference intervals.

  • State 3.2% (0.109M) sodium citrate as standard coagulation anticoagulant
  • Apply 9:1 blood-to-anticoagulant fill volume requirement
  • Recognize underfilled tube and high hematocrit citrate dilution effects
  • Describe centrifugation, storage, and reject criteria per institutional SOP