Pre-Transfusion Testing

This Medical Laboratory Science lesson in Blood Bank supports laboratory science learning and laboratory interpretation for medical laboratory students and professionals.

Walk the laboratory pathway from sample receipt and specimen acceptability through ABO/Rh typing and the antibody screen to the decision to crossmatch or issue.

Intermediate30 min read15 sectionsBlood Bank
Section 1 of 150%

Learning Objectives

Getting started

Section 1 of 15

Learning Objectives

Learning Objectives

Section: Learning Objectives

Each objective below describes a transfusion-service laboratory competency, from sample receipt through compatibility testing to documented blood issue.

  • Verify the specimen and requisition identity/acceptability criteria that must be satisfied before pre-transfusion testing begins
  • Perform and interpret ABO/Rh typing and the antibody screen as the core pre-transfusion serologic workup
  • Determine, from screen and antibody-history results, whether a unit proceeds to crossmatch (and by which method) or is held for further workup