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Pretransfusion Crossmatching

This Medical Laboratory Science lesson in Blood Bank supports laboratory science learning and laboratory interpretation for medical laboratory students and professionals.

Purpose of the major crossmatch, differences between serologic and electronic methods, and how antibody screen and history determine which method applies before unit release.

Intermediate26 min read15 sectionsBlood Bank
Section 1 of 150%

Learning Objectives

Getting started

Section 1 of 15

Learning Objectives

Learning Objectives

Section: Learning Objectives

Each objective below describes a transfusion-service laboratory competency, from sample receipt through compatibility testing to documented blood issue.

  • Explain the purpose of the major crossmatch as the final laboratory check between patient plasma and a specific donor unit before release
  • Differentiate serologic crossmatch methods (immediate spin, antihuman globulin) from the electronic (computer) crossmatch
  • Select the appropriate crossmatch method for a given patient based on the antibody screen result and antibody history

Section 1 of 15