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Anaphylactic Transfusion Reactions

This Medical Laboratory Science lesson in Blood Bank supports laboratory science learning and laboratory interpretation for medical laboratory students and professionals.

Perform the laboratory's investigation and communication role when anaphylaxis is suspected during transfusion, recognizing systemic severity, reviewing IgA-related history, and reviewing washed/IgA-deficient product attributes, without describing emergency medication administration.

Advanced26 min read15 sectionsBlood Bank
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Learning Objectives

Getting started

Section 1 of 15

Learning Objectives

Learning Objectives

Section: Learning Objectives

Each objective below describes a transfusion-service laboratory competency, investigating and interpreting adverse transfusion reactions, not delivering bedside treatment.

  • Recognize the systemic features that distinguish a suspected anaphylactic transfusion reaction from a routine allergic reaction, and describe the laboratory's immediate notification and documentation role
  • Explain the IgA-deficiency/anti-IgA mechanism proposed for some severe anaphylactic transfusion reactions and describe the laboratory's history-review role, not treatment
  • Describe washed and IgA-deficient product attributes as laboratory/blood-supplier stewardship considerations for future transfusions, distinct from bedside emergency management

Section 1 of 15