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Positive and Negative Controls

This Medical Laboratory Science lesson in Molecular Diagnostics supports laboratory science learning and laboratory interpretation for medical laboratory students and professionals.

Explain positive and negative controls used in molecular quality practice and what failures mean for result release.

Advanced8 min read15 sectionsMolecular Diagnostics
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Learning Objectives

Getting started

Section 1 of 15

Learning Objectives

Learning Objectives

Section: Learning Objectives

Each objective is an everyday molecular laboratory quality skill, not a full accreditation curriculum.

  • State what positive and negative (including no-template) controls protect in molecular runs
  • Decide that failed positive or negative controls stop routine patient result release until the SOP is followed
  • Distinguish routine control QC from verification, validation, and external assessment at an introductory level

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