Immediate Spin Crossmatch

This Medical Laboratory Science lesson in Blood Bank supports laboratory science learning and laboratory interpretation for medical laboratory students and professionals.

Perform the immediate-spin crossmatch to detect ABO incompatibility at room temperature, and recognize when an antiglobulin (AHG) phase must still be added despite a negative immediate-spin result.

Intermediate26 min read15 sectionsBlood Bank
Section 1 of 150%

Learning Objectives

Getting started

Section 1 of 15

Learning Objectives

Learning Objectives

Section: Learning Objectives

Each objective below describes a transfusion-service laboratory competency, from sample receipt through compatibility testing to documented blood issue.

  • Describe the immediate-spin crossmatch procedure and the specific type of incompatibility it is designed to detect
  • Explain why immediate spin alone is an appropriate method only for patients with a negative antibody screen and no history of a clinically significant antibody
  • Identify when the antiglobulin (AHG) phase must be added to a crossmatch despite a negative immediate-spin result